Project Voice—Improving Health Outcomes for PAD patients


Peripheral artery disease (PAD) is a chronic and disabling disease that affects about 10 million Americans, including up to 20% of people over 65. PAD costs $21 billion per year to treat and is a leading cause of disability and amputation, often resulting in death. Several widespread issues contribute to PAD:

  • Physical inactivity worsens symptoms, mobility, and underlying disease
  • Lack of information limits patients’ understanding of their diagnosis and how to manage their condition
  • Low patient engagement delays treatment and reduces compliance


Exercise (walking) therapy has been shown to significantly improve health outcomes in symptomatic PAD patients. While supervised exercise therapy (SET) in a clinical setting can markedly improve walking endurance in symptomatic PAD patients, they often find it difficult to regularly attend their prescribed exercise sessions. Studies have shown that home-based exercise therapy can improve walking endurance and claudication (leg pain) onset time in PAD patients.

With that in mind, Project Voice was designed to offer patients home-based exercise therapy by providing them with a walking activity tracker and a patient interface that offers educational and engagement resources and surveys to collect patient feedback on their health and quality of life.

Vascular Cures has supported two feasibility studies and is currently working with multiple partners to advance research to bring digitally-enabled home-based exercise therapy (DHET) to patients with PAD.  Our partners in this effort are leading experts in the fields of PAD, exercise therapy, behavior modification, and digital technology who share our goal to develop a long-term, scalable care solution that improves health outcomes, reduces costs to the system, and enables increased access to quality care.

Steve’s Story – Walking Helped Me Avoid Surgery

“When I was diagnosed with PAD, my doctor recommended bypass surgery. I got a second opinion and that doctor told me ‘I really can’t improve your quality of life with surgery. What you need to do is start walking.’  I started walking, and I got up to 2-3 miles in a day. That’s not to say I wasn’t experiencing pain along the way at different times, but the more I walked the better my circulation became. Fast forward to today – 10 years later – I am 74, and I’m quite active. I no longer have pain in my lower legs and do not need surgery.”

Watch Steve’s story:

Feasibility Studies

Matthew Corriere, MD, MS (University of Michigan) was the Principal Investigator leading two exploratory studies at the University of Michigan and Wake Forest University. The studies evaluated the feasibility of a digital health platform coupled with walking activity tracking for patients with PAD and symptoms of claudication.

Project Voice Publications:


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