Project Voice


Project Voice was designed to improve outcomes for PAD patients by advancing the field of digitally enabled home-based exercise therapy (DHET) and the use of patient-reported outcome (PRO) measures in PAD care and research. Exercise (walking) therapy has been shown to significantly improve health outcomes in symptomatic PAD patients. Vascular Cures has supported two feasibility studies and is currently at work to design a breakthrough, large-scale study to improve the health outcomes of patients with peripheral artery disease (PAD) in a way that is scalable and cost-effective.

Peripheral artery disease (PAD)is a chronic and disabling disease that affects about 10 million Americans, including up to 20% of people over 65. PAD costs $21 billion per year to treat and is a leading cause of disability and amputation, often resulting in death. Several widespread issues contribute to PAD:

  • Physical inactivity worsens symptoms, mobility and underlying disease
  • Low patient engagement delays treatment and reduces compliance
  • Lack of information limits patients’ understanding of their diagnosis and capacity for self-health management


While supervised exercise therapy (SET) in a clinical setting can markedly improve walking endurance in symptomatic PAD patients, they often find it difficult to regularly attend their prescribed exercise sessions.Studies have shown that home-based exercise therapy, when the program is followed, can improve walking endurance and claudication (leg pain) onset time in PAD patients.


We have partnered with leading experts in the fields of PAD, exercise therapy, behavior modification and digital technology to design a digitally enabled home-based exercise therapy (DHET) program that we believe could be a long-term, scalable care solution that creates value for both patients and health systems/care providers. The Voice approach to home-based exercise therapy utilizes an activity tracker, a patient portal(web and application), and patient engagement resources to provide:

  • Real-time tracking of PAD patients’walking activity
  • Real-time reporting of activity data back to patients in a way that is visually interesting and engaging
  • Scheduling and granular recording of exercise compliance, duration, and effort
  • Continuous reporting of data to care, providers, to objectively track changes in both passive activity as well as exercise tolerance
  • A way to capture the patient-reported quality of life outcomes from patients (i.e. surveys & questionnaires)
  • Educational materials to patients which increases empowerment and engagement


Feasibility Studies

Matthew Corriere, MD, MS (University of Michigan) was the Principal Investigator leading two exploratory studies at the University of Michigan and Wake Forest University. The studies evaluated the feasibility of adigital health platform coupled with walking activity tracking for patients with Peripheral Artery Disease (PAD) and symptoms of claudication


Project Voice Publications:
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